Natural and artificial selection

Biology A2 · Selection and evolution. The idea in plain words, the rules to remember, the mistake to avoid and a worked example, written and checked by Mega Lecture.

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The idea

Populations can produce far more offspring than the environment can support, so individuals compete. Those with the best adapted phenotypes are more likely to survive, reproduce and pass on their alleles. Over generations the frequency of these alleles rises. This is natural selection.

Selection can keep the average (stabilising), push the population towards one extreme (directional) or favour both extremes (disruptive). Allele frequencies can also change by chance. This is genetic drift, and it is strongest in small populations, such as founders of a new population or survivors of a bottleneck.

In selective breeding humans choose the parents, generation after generation, to improve a feature they want.

Rules to remember

Common mistake

Students take the percentage with the recessive phenotype as q. That percentage is q2, so take its square root first.

Worked example

In a population of 250 mice, 4% have a recessive coat colour. Assuming Hardy–Weinberg equilibrium, how many mice are expected to be heterozygous?

  1. q2 = 0.04, so q = √0.04 = 0.2.
  2. p = 1 − 0.2 = 0.8.
  3. 2pq = 2 × 0.8 × 0.2 = 0.32.
  4. Number heterozygous = 0.32 × 250 = 80.

Answer: 80 mice are expected to be heterozygous.

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