The gas exchange system

Biology AS · Gas exchange. The idea in plain words, the rules to remember, the mistake to avoid and a worked example, written and checked by Mega Lecture.

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The idea

Air passes down the trachea, into the two bronchi, through smaller and smaller bronchioles and into the alveoli, where gas exchange takes place. Each alveolus is wrapped in a network of capillaries.

The tissues change along this path. The trachea and bronchi have cartilage to hold them open, and a lining of ciliated epithelium with goblet cells. Bronchioles have no cartilage but have smooth muscle. Alveoli have a wall of squamous epithelium with elastic fibres.

Oxygen diffuses from the alveolar air into the blood, and carbon dioxide diffuses the other way. The path is very short: one thin alveolar cell and one thin capillary cell. Ventilation and blood flow keep the concentration gradients steep.

Rules to remember

Common mistake

Writing that cilia trap or filter dust. Mucus traps the particles; cilia only move the mucus.

Worked example

A transverse section of an airway about 0.8 mm across shows a folded lining of ciliated epithelium and a ring of smooth muscle, but no cartilage. Which part of the gas exchange system is it?

  1. No cartilage rules out the trachea and the bronchi.
  2. Alveoli have a wall of squamous epithelium with no cilia and no smooth muscle, so it is not an alveolus.
  3. An airway with smooth muscle and ciliated epithelium but no cartilage is a bronchiole.

Answer: A bronchiole.

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