In fission a heavy nucleus splits into two smaller nuclei and a few neutrons. It can happen on its own (spontaneous fission) or after the nucleus absorbs a neutron (induced fission). The products have a higher binding energy per nucleon, so mass is lost and energy is released, mostly as kinetic energy of the fission fragments.
The neutrons released can cause more fissions. This is a chain reaction. It keeps going if, on average, at least one neutron from each fission causes another. The fuel must exceed a critical mass, or too many neutrons escape.
A power station controls the chain reaction and uses the thermal energy to make steam, which drives turbines.