Genetic inheritance, inherited disorders and sex determination

Biology · Inheritance, variation and evolution. The idea in plain words, the rules to remember, the mistake to avoid and a worked example, written and checked by Mega Lecture.

Test this topic freeAll Biology topics

The idea

Most genes have different forms called alleles. You inherit one allele of each gene from each parent, so you have two. The pair of alleles you have is your genotype. The characteristic that shows is your phenotype.

A dominant allele shows even if only one copy is present. A recessive allele shows only when both copies are recessive. A Punnett square lists the gametes of each parent and shows every possible combination in the offspring, so you can read off ratios and probabilities.

Sex is decided by one pair of chromosomes. Females are XX and males are XY.

Rules to remember

Common mistake

A Punnett square gives probabilities, not promises. A 0.25 chance applies to every child separately, so it does not mean exactly one child in four will be affected.

Worked example

Polydactyly is caused by a dominant allele, D. Both parents are heterozygous (Dd). What is the probability that their child has polydactyly?

  1. Each parent makes gametes D and d.
  2. The Punnett square gives DD, Dd, Dd and dd.
  3. DD and Dd have the dominant allele, so 3 of the 4 combinations have polydactyly.
  4. Probability = 3 ÷ 4 = 0.75.

Answer: 0.75 (75%).

Ask about this

Type what you are stuck on. The helper finds the explanation, worked examples and the notes to read, free and instant.

Read the full notes

Keep going

← Reproduction, meiosis and DNAVariation, evolution and genetic technologies →Take a Biology test